For research use only. Not for therapeutic Use.
Efaroxan hydrochloride（Cat No.:I010302）is a potent α₂-adrenergic receptor antagonist and imidazoline receptor ligand used in pharmacological research. It blocks presynaptic α₂-adrenoceptors, enhancing norepinephrine release and promoting sympathetic nervous activity. Additionally, efaroxan acts on imidazoline I₁ receptors, contributing to its antihypertensive and insulinotropic effects. It has been studied for its potential in managing type 2 diabetes by stimulating insulin secretion from pancreatic β-cells. The hydrochloride salt improves solubility and handling in experimental settings. Efaroxan is widely used to explore neurochemical pathways and autonomic regulation in cardiovascular and metabolic research models.
| CAS Number | 89197-00-2 |
| Synonyms | 2-(2-ethyl-3H-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole;hydrochloride |
| Molecular Formula | C13H17ClN2O |
| Purity | ≥95% |
| IUPAC Name | 2-(2-ethyl-3H-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole;hydrochloride |
| InChI | InChI=1S/C13H16N2O.ClH/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13;/h3-6H,2,7-9H2,1H3,(H,14,15);1H |
| InChIKey | DWOIUCRHVWIHAH-UHFFFAOYSA-N |
| SMILES | CCC1(CC2=CC=CC=C2O1)C3=NCCN3.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
