E(c(RGDfK))2

• CAT Number: I040404
• CAS Number: 250612-47-6
• Molecular Formula: C59H87N19O16
• Molecular Weight: 1318.44
• Purity: ≥95%
• Synonyms: 2-[(2S,5R,8S,11S)-8-[4-[[(4S)-4-amino-5-[4-[(2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]butylamino]-5-oxopentanoyl]amino]butyl]-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
• InChI: InChI=1S/C59H87N19O16/c60-35(49(86)66-24-10-8-18-39-53(90)74-37(20-12-26-68-59(63)64)51(88)70-32-46(81)72-43(30-48(84)85)57(94)78-41(55(92)76-39)28-34-15-5-2-6-16-34)21-22-44(79)65-23-9-7-17-38-52(89)73-36(19-11-25-67-58(61)62)50(87)69-31-45(80)71-42(29-47(82)83)56(93)77-40(54(91)75-38)27-33-13-3-1-4-14-33/h1-6,13-16,35-43H,7-12,17-32,60H2,(H,65,79)(H,66,86)(H,69,87)(H,70,88)(H,71,80)(H,72,81)(H,73,89)(H,74,90)(H,75,91)(H,76,92)(H,77,93)(H,78,94)(H,82,83)(H,84,85)(H4,61,62,67)(H4,63,64,68)/t35-,36-,37-,38-,39-,40+,41+,42-,43-/m0/s1
• InChIKey: HBRYUNRKUGWZGH-LMKMLFLWSA-N
• SMILES: C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCNC(=O)CCC(C(=O)NCCCCC2C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2)CC3=CC=CC=C3)CC(=O)O)CCCN=C(N)N)N)CC4=CC=CC=C4)CC(=O)O

E(c(RGDfK))₂(CAT: I040404) is a cyclic RGD peptide dimer specifically engineered for high-affinity binding to integrin αvβ3 and αvβ5 receptors, which are overexpressed in tumor vasculature and certain cancer cells. The dimeric structure enhances receptor binding avidity and selectivity, making it an effective tool for tumor targeting, angiogenesis inhibition, and molecular imaging applications. E(c(RGDfK))₂ is widely used in oncology research, targeted drug delivery, and the development of theranostic agents. Its stability and receptor specificity support reliable performance in both in vitro and in vivo studies. Supplied at high purity, it is ideal for advanced integrin-related biomedical research.