For research use only. Not for therapeutic Use.
Eact（Cat No.:I011045）is a pharmacological activator of ATP-sensitive potassium (KATP) channels and large-conductance calcium-activated potassium (BKCa) channels, making it a valuable research tool in cardiovascular and neurophysiological studies. By opening these potassium channels, Eact promotes membrane hyperpolarization, leading to smooth muscle relaxation, vasodilation, and modulation of neuronal excitability. It has been used to investigate protective mechanisms in ischemia, hypertension, and metabolic regulation. Eact’s dual activity provides insights into potassium channel physiology and supports the exploration of novel therapeutic strategies targeting cardiovascular and neurological disorders.
| CAS Number | 461000-66-8 |
| Synonyms | 3,4,5-trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide |
| Molecular Formula | C22H24N2O5S |
| Purity | ≥95% |
| IUPAC Name | 3,4,5-trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide |
| InChI | InChI=1S/C22H24N2O5S/c1-26-11-10-24(22-23-17(14-30-22)15-8-6-5-7-9-15)21(25)16-12-18(27-2)20(29-4)19(13-16)28-3/h5-9,12-14H,10-11H2,1-4H3 |
| InChIKey | ZUXNHFFVQWADJL-UHFFFAOYSA-N |
| SMILES | COCCN(C1=NC(=CS1)C2=CC=CC=C2)C(=O)C3=CC(=C(C(=C3)OC)OC)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
