E3 Ligase Ligand-Linker Conjugates 19

  • CAT Number: I013174
  • CAS Number: 1799711-24-2
  • Molecular Formula: C₁₉H₂₂N₄O₆
  • Molecular Weight: 402.4
  • Purity: ≥95%
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E3 Ligase Ligand-Linker Conjugate 19(CAT: I013174) refers to a specific compound that belongs to a class of molecules known as E3 ligase ligand-linker conjugates. These conjugates are designed to selectively bind to E3 ligases, which are enzymes involved in the ubiquitination process, and facilitate the targeted degradation of specific proteins within cells. E3 Ligase Ligand-Linker Conjugate 19 is constructed with a ligand moiety that binds to the E3 ligase and a linker component that connects it to a target protein for degradation.

Catalog Number I013174
CAS Number 1799711-24-2
Molecular Formula


Purity 95%
Target Epigenetic Reader DomainE3 Ligase Ligand-Linker Conjugate
Solubility DMSO
IUPAC Name N-(4-aminobutyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide
InChI InChI=1S/C19H22N4O6/c20-8-1-2-9-21-15(25)10-29-13-5-3-4-11-16(13)19(28)23(18(11)27)12-6-7-14(24)22-17(12)26/h3-5,12H,1-2,6-10,20H2,(H,21,25)(H,22,24,26)

[1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2017 Mar 24.<br>[2]. James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

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