(E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

• CAT Number: L018397
• CAS Number: 1168150-46-6
• Molecular Formula: C18H15NO4
• Molecular Weight: 309.31
• Purity: ≥95%
• IUPAC Name: methyl (3E)-3-[methoxy(phenyl)methylidene]-2-oxo-1H-indole-6-carboxylate
• InChI: InChI=1S/C18H15NO4/c1-22-16(11-6-4-3-5-7-11)15-13-9-8-12(18(21)23-2)10-14(13)19-17(15)20/h3-10H,1-2H3,(H,19,20)/b16-15+
• InChIKey: WUVZENIISJMEHI-FOCLMDBBSA-N
• SMILES: CO/C(=C/1\C2=C(C=C(C=C2)C(=O)OC)NC1=O)/C3=CC=CC=C3

(E)-Methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate(CAT: L018397) is a synthetic oxindole derivative featuring a conjugated methoxyphenylmethylene moiety and a methyl ester group at the 6-position. This compound is structurally related to bioactive heterocycles found in various pharmaceutical leads and natural products. Its electron-rich indolinone core and extended conjugation make it a valuable scaffold for medicinal chemistry, especially in designing inhibitors targeting kinases, proteases, and cancer-related pathways. It is also used in structure–activity relationship (SAR) studies, molecular probe development, and synthetic organic chemistry. The (E)-configuration promotes geometric stability and electronic interactions favorable for drug-like behavior and receptor binding investigations.