For research use only. Not for therapeutic Use.
Dynole 2-24（Cat No.:I045185）is a potent, cell-permeable inhibitor of dynamin GTPases, key enzymes mediating clathrin-dependent endocytosis and vesicle trafficking. By blocking dynamin’s GTP hydrolysis, Dynole 2-24 prevents membrane fission events, thereby inhibiting endocytic uptake of receptors, ligands, and viruses. It is widely used to study intracellular trafficking, receptor recycling, and endocytosis-dependent signaling pathways. Dynole 2-24 has applications in neuroscience, virology, and cancer research, enabling targeted disruption of dynamin function to elucidate its role in cellular processes. Its high potency and reversibility make it a versatile chemical biology tool.
| CAS Number | 1416313-72-8 |
| Synonyms | N-[[1-[3-(dimethylamino)propyl]indol-3-yl]methyl]decan-1-amine |
| Molecular Formula | C24H41N3 |
| Purity | ≥95% |
| IUPAC Name | N-[[1-[3-(dimethylamino)propyl]indol-3-yl]methyl]decan-1-amine |
| InChI | InChI=1S/C24H41N3/c1-4-5-6-7-8-9-10-13-17-25-20-22-21-27(19-14-18-26(2)3)24-16-12-11-15-23(22)24/h11-12,15-16,21,25H,4-10,13-14,17-20H2,1-3H3 |
| InChIKey | ZXKCYZJGHXORKJ-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCNCC1=CN(C2=CC=CC=C21)CCCN(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
