For research use only. Not for therapeutic Use.
DX3-213B（Cat No.:I044052）is a potent and selective inhibitor of casein kinase 1 delta and epsilon (CK1δ/ε), serine/threonine kinases involved in regulating circadian rhythms, Wnt signaling, and cellular proliferation. By targeting CK1δ/ε, DX3-213B disrupts key phosphorylation events that influence clock gene expression and β-catenin stability, making it valuable in circadian biology, cancer, and neurodegenerative disease research. This compound is particularly useful for exploring the role of CK1 isoforms in sleep disorders, mood regulation, and tumor progression. DX3-213B enables investigation into therapeutic strategies involving the modulation of kinase-driven signaling pathways.
| CAS Number | 2749555-66-4 |
| Synonyms | (4,4-difluoropiperidin-1-yl)-[(3R)-1-(4-propan-2-ylsulfonylphenyl)sulfonylpiperidin-3-yl]methanone |
| Molecular Formula | C20H28F2N2O5S2 |
| Purity | ≥95% |
| IUPAC Name | (4,4-difluoropiperidin-1-yl)-[(3R)-1-(4-propan-2-ylsulfonylphenyl)sulfonylpiperidin-3-yl]methanone |
| InChI | InChI=1S/C20H28F2N2O5S2/c1-15(2)30(26,27)17-5-7-18(8-6-17)31(28,29)24-11-3-4-16(14-24)19(25)23-12-9-20(21,22)10-13-23/h5-8,15-16H,3-4,9-14H2,1-2H3/t16-/m1/s1 |
| InChIKey | HLSJMSNPBRGRGL-MRXNPFEDSA-N |
| SMILES | CC(C)S(=O)(=O)C1=CC=C(C=C1)S(=O)(=O)N2CCC[C@H](C2)C(=O)N3CCC(CC3)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
