Duvakitug

• CAT Number: I040655
• CAS Number: 2750005-84-4
• Purity: ≥95%

Duvakitug(CAT: I040655) is an investigational monoclonal antibody that targets interleukin-1 receptor accessory protein (IL1RAP), a co-receptor involved in pro-inflammatory cytokine signaling pathways such as IL-1, IL-33, and IL-36. By binding IL1RAP, Duvakitug blocks downstream signaling cascades that drive chronic inflammation, making it a potential therapeutic agent for autoimmune and inflammatory diseases, as well as certain hematologic malignancies. Its mechanism supports modulation of innate immunity, with ongoing research exploring its role in myeloproliferative disorders and solid tumors.