Dusquetide

• CAT Number: I006558
• CAS Number: 931395-42-5
• Molecular Formula: C25H47N9O5
• Molecular Weight: 553.70
• Purity: ≥95%
• Synonyms: (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
• IUPAC Name: (2S)-1-[(2S)-2-[[(3S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
• InChI: InChI=1S/C25H47N9O5/c1-6-14(4)19(33-21(36)16(26)9-7-11-30-25(28)29)23(38)32-18(13(2)3)24(39)34-12-8-10-17(34)22(37)31-15(5)20(27)35/h13-19H,6-12,26H2,1-5H3,(H2,27,35)(H,31,37)(H,32,38)(H,33,36)(H4,28,29,30)/t14-,15-,16-,17-,18-,19?/m0/s1
• InChIKey: ZUJBBVJXXYRPFS-OUROWQTJSA-N
• SMILES: CC[C@H](C)C(C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N)NC(=O)[C@H](CCCN=C(N)N)N

Dusquetide（Cat No.:I006558）is a synthetic innate defense regulator (IDR) peptide that modulates the body’s natural immune response to infection and inflammation. Unlike traditional antimicrobials, it does not directly kill pathogens but enhances host defense by reducing pro-inflammatory cytokines, promoting anti-inflammatory signaling, and accelerating tissue healing. Dusquetide has been investigated in clinical studies for oral mucositis and other inflammatory conditions, demonstrating efficacy in reducing symptoms and improving recovery. As a novel immunomodulatory therapeutic, dusquetide represents a promising strategy for treating inflammation-driven disorders while minimizing resistance development.