DSPE-PEG6-Mal

• CAT Number: I044633
• Molecular Formula: C60H111N2O17P
• Molecular Weight: 1163.50
• Purity: ≥95%
• Synonyms: [(2R)-3-[2-[3-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate
• InChI: InChI=1S/C60H111N2O17P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-59(66)76-53-55(79-60(67)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)54-78-80(68,69)77-41-38-61-56(63)37-40-70-43-45-72-47-49-74-51-52-75-50-48-73-46-44-71-42-39-62-57(64)35-36-58(62)65/h35-36,55H,3-34,37-54H2,1-2H3,(H,61,63)(H,68,69)/t55-/m1/s1
• InChIKey: CRTPHYSBAGPSHQ-KZRJWCEASA-N
• SMILES: CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCNC(=O)CCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCCCCCC

DSPE-PEG6-Mal（Cat No.:I044633）is a functionalized phospholipid composed of DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine), a six-unit polyethylene glycol (PEG6) spacer, and a terminal maleimide group. The DSPE tail allows stable integration into lipid bilayers or liposomes, while the PEG6 chain provides hydrophilicity and steric flexibility. The maleimide moiety enables site-specific conjugation to thiol-containing molecules via Michael addition. This amphiphilic molecule is ideal for constructing targeted liposomes, nanoparticle surfaces, and drug delivery systems, offering biocompatibility, prolonged circulation time, and the ability to attach ligands, peptides, or antibodies for biomedical and pharmaceutical applications.