For research use only. Not for therapeutic Use.
DSPE-PEG2000-Maleimide（Cat No.:I045293）is an amphiphilic phospholipid–polyethylene glycol conjugate used for targeted drug delivery and nanomedicine applications. It consists of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) linked to a 2 kDa PEG chain terminated with a maleimide group. The maleimide enables site-specific conjugation to thiol-containing ligands, antibodies, or peptides, facilitating targeted nanoparticle or liposome functionalization. The DSPE moiety anchors into lipid bilayers, while PEG2000 enhances circulation time by reducing opsonization and immune clearance. This versatile reagent is widely employed in developing long-circulating, ligand-directed liposomal drug carriers and other advanced nanotherapeutic delivery platforms.
| CAS Number | 474922-22-0 |
| Purity | ≥95% |
| IUPAC Name | sodium;[(2R)-2,3-di(octadecanoyloxy)propyl] 2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxycarbonylamino]ethyl phosphate;methane |
| InChI | InChI=1S/C53H96N3O14P.CH4.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-51(60)67-45-47(70-52(61)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)46-69-71(63,64)68-42-39-55-53(62)66-44-43-65-41-38-54-48(57)37-40-56-49(58)35-36-50(56)59;;/h35-36,47H,3-34,37-46H2,1-2H3,(H,54,57)(H,55,62)(H,63,64);1H4;/q;;+1/p-1/t47-;;/m1../s1 |
| InChIKey | HGHUOBIWDTYIOX-ZJYNJCDSSA-M |
| SMILES | C.CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCCNC(=O)OCCOCCNC(=O)CCN1C(=O)C=CC1=O)OC(=O)CCCCCCCCCCCCCCCCC.[Na+] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
