For research use only. Not for therapeutic Use.
DSPE-N₃ (Cat No.: I042510) is an azide-functionalized phospholipid commonly used in bioorthogonal chemistry and nanomedicine. The DSPE moiety enables incorporation into liposomes, micelles, or lipid bilayers, while the terminal azide group allows copper-catalyzed or copper-free click chemistry with alkyne-containing molecules. DSPE-N₃ is widely employed for site-specific conjugation of targeting ligands, peptides, or polymers to drug delivery systems. Its versatility and bioorthogonal reactivity make it ideal for developing functionalized nanocarriers, imaging agents, and targeted therapeutics in biomedical and pharmaceutical research.
| CAS Number | 2839508-98-2 |
| Synonyms | [(2R)-3-[2-[(2-azidoacetyl)amino]ethoxy-hydroxyphosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate |
| Molecular Formula | C43H83N4O9P |
| Purity | ≥95% |
| InChI | InChI=1S/C43H83N4O9P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-42(49)53-38-40(39-55-57(51,52)54-36-35-45-41(48)37-46-47-44)56-43(50)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h40H,3-39H2,1-2H3,(H,45,48)(H,51,52)/t40-/m1/s1 |
| InChIKey | ZIQJHLAPBLHPFF-RRHRGVEJSA-N |
| SMILES | CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)CN=[N+]=[N-])OC(=O)CCCCCCCCCCCCCCCCC |
| Reference | [1]. Janssen, et al. Compounds for regulating trained immunity, and their methods of use. Patent. WO2022198101A1. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
