For research use only. Not for therapeutic Use.
DS20362725(Cat No.:I045202)is a potent, selective inhibitor of the sodium-calcium exchanger 1 (NCX1), a transmembrane protein that regulates intracellular calcium homeostasis by exchanging Ca²⁺ for Na⁺ across the plasma membrane. By blocking NCX1 activity, DS20362725 modulates calcium signaling, influencing processes such as cardiac muscle contraction, neuronal excitability, and vascular tone. It is a valuable research tool for investigating calcium-dependent physiological and pathological mechanisms, including heart failure, ischemia-reperfusion injury, and neurodegenerative diseases. DS20362725 holds therapeutic potential for conditions driven by abnormal calcium handling and excitotoxicity, offering targeted modulation of cellular calcium dynamics.
CAS Number | 2735803-20-8 |
Synonyms | 2-tert-butyl-4-(2,3-dimethylbenzimidazol-5-yl)oxyphenol |
Molecular Formula | C19H22N2O2 |
Purity | ≥95% |
IUPAC Name | 2-tert-butyl-4-(2,3-dimethylbenzimidazol-5-yl)oxyphenol |
InChI | InChI=1S/C19H22N2O2/c1-12-20-16-8-6-14(11-17(16)21(12)5)23-13-7-9-18(22)15(10-13)19(2,3)4/h6-11,22H,1-5H3 |
InChIKey | LQWRSCHPPDJXLC-UHFFFAOYSA-N |
SMILES | CC1=NC2=C(N1C)C=C(C=C2)OC3=CC(=C(C=C3)O)C(C)(C)C |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |