For research use only. Not for therapeutic Use.
DPO-1 (Cat No.:I010578) is a selective inhibitor of voltage-gated potassium channels, particularly Kv1.5, which is predominantly expressed in atrial tissue. By blocking Kv1.5, DPO-1 prolongs atrial action potential duration without significantly affecting ventricular repolarization, making it a promising tool in atrial-selective antiarrhythmic research. It is widely used in cardiac electrophysiology studies to investigate atrial fibrillation mechanisms and the role of Kv channels in cardiac repolarization. DPO-1 also exhibits some inhibitory activity on other Kv channels, such as Kv1.3, making it relevant in immunological and vascular research as well.
| CAS Number | 43077-30-1 |
| Synonyms | [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene |
| Molecular Formula | C22H29OP |
| Purity | ≥95% |
| IUPAC Name | [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene |
| InChI | InChI=1S/C22H29OP/c1-17(2)21-15-14-18(3)16-22(21)24(23,19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-13,17-18,21-22H,14-16H2,1-3H3/t18-,21+,22+/m1/s1 |
| InChIKey | BPCNGVCAHAIZEE-COPCDDAFSA-N |
| SMILES | C[C@@H]1CC[C@H]([C@H](C1)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
