DPDPE TFA

• CAT Number: I014842
• CAS Number: 172888-59-4
• Molecular Formula: C32H40F3N5O9S2
• Molecular Weight: 759.81
• Purity: ≥95%
• IUPAC Name: (4S,7S,13S)-13-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C30H39N5O7S2.C2HF3O2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29;3-2(4,5)1(6)7/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42);(H,6,7)/t20-,21-,23-,24-;/m0./s1
• InChIKey: LUVILUYVBUMMRG-JZHXPYGKSA-N
• SMILES: CC1([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SS1)(C)C)C(=O)O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)C.C(=O)(C(F)(F)F)O

DPDPE TFA（Cat No.:I014842）is the trifluoroacetate salt form of the synthetic enkephalin analog DPDPE ([D-Pen²,D-Pen⁵]-enkephalin). This cyclic peptide is a highly selective agonist for the δ-opioid receptor, widely used in pharmacological research to explore opioid receptor function, signal transduction, and analgesic mechanisms. The incorporation of two D-penicillamine residues stabilizes its conformation, enhancing δ-receptor affinity while reducing susceptibility to enzymatic degradation. DPDPE TFA serves as a valuable tool for investigating pain modulation, neuroprotection, and the therapeutic potential of δ-opioid receptor targeting in central nervous system disorders.