DOTA-PEG5-amine

• CAT Number: I045942
• Molecular Formula: C28H54N6O12
• Molecular Weight: 666.76
• Purity: ≥95%
• Synonyms: 2-[4-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-2-oxoethyl]-7,10-bis(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
• InChI: InChI=1S/C28H54N6O12/c29-1-11-42-13-15-44-17-19-46-20-18-45-16-14-43-12-2-30-25(35)21-31-3-5-32(22-26(36)37)7-9-34(24-28(40)41)10-8-33(6-4-31)23-27(38)39/h1-24,29H2,(H,30,35)(H,36,37)(H,38,39)(H,40,41)
• InChIKey: MALHBNFXIUVFNS-UHFFFAOYSA-N
• SMILES: C1CN(CCN(CCN(CCN1CC(=O)NCCOCCOCCOCCOCCOCCN)CC(=O)O)CC(=O)O)CC(=O)O

DOTA-PEG5-amine（Cat No.:I045942）is a multifunctional chelating linker designed for radiolabeling, imaging, and targeted delivery applications. It incorporates a DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) moiety, which strongly coordinates metal ions such as ^64Cu, ^68Ga, or ^177Lu, making it ideal for PET, SPECT, and radiotherapeutic studies. The PEG5 spacer enhances solubility, reduces steric hindrance, and improves biocompatibility, while the terminal amine group enables versatile conjugation to biomolecules, peptides, or polymers. This reagent is widely applied in nuclear medicine, molecular imaging, and drug delivery research for constructing stable, functionalized radioconjugates.