Docetaxel

• CAT Number: A000806
• CAS Number: 114977-28-5
• Molecular Formula: C₄₃H₅₃NO₁₄
• Molecular Weight: 807.88
• Purity: ≥95%
• Synonyms: RP56976, NSC 628503
• Target: Microtubule/Tubulin
• Solubility: >40.4mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate
• InChI: InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,
• InChIKey: ZDZOTLJHXYCWBA-VCVYQWHSSA-N
• SMILES: CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Docetaxel（Cat No.:A000806）is a potent chemotherapeutic agent used primarily in the treatment of various cancers, including breast, prostate, lung, and head and neck cancers. As a member of the taxane family, it works by stabilizing microtubules, inhibiting cell division, and promoting apoptosis in cancer cells. Known for its efficacy in both early and advanced stages of cancer, docetaxel is often utilized in combination with other drugs to enhance treatment outcomes. Its formulation improves bioavailability, making it a key option in oncological therapies.

Reference

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