Dimethyl Malonate

• CAT Number: R045851
• CAS Number: 108-59-8
• Molecular Formula: C5H8O4
• Molecular Weight: 132.12
• Purity: ≥95%
• Synonyms: Propanedioic Acid 1,3-Dimethyl Ester; Malonic Acid Dimethyl Ester; Propanedioic Acid Dimethyl Ester; Dimethyl 1,3-Propanedioate; Dimethyl Propanedioate; Methyl Malonate; NSC 620046
• Target: Apoptosis
• Storage: -20°C
• IUPAC Name: dimethyl propanedioate
• InChI: InChI=1S/C5H8O4/c1-8-4(6)3-5(7)9-2/h3H2,1-2H3
• InChIKey: BEPAFCGSDWSTEL-UHFFFAOYSA-N
• SMILES: COC(=O)CC(=O)OC

Dimethyl Malonate (Cat No.: R045851) is a diester of malonic acid, appearing as a colorless, fruity-smelling liquid. It is widely used in organic synthesis as a versatile building block, particularly in Knoevenagel condensations, alkylation reactions, and the synthesis of barbiturates, vitamins, and pharmaceuticals. Its two ester groups make it highly reactive toward nucleophiles and enolate formation. Dimethyl malonate also serves in the production of agrochemicals and dyes. It should be handled with care due to its flammability and potential health effects upon inhalation.