Dimethyl lithospermate B

• CAT Number: R072486
• CAS Number: 875313-64-7
• Molecular Formula: C38H34O16
• Molecular Weight: 746.67
• Purity: ≥95%
• Synonyms: [(2R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl] (2S,3S)-2-(3,4-dihydroxyphenyl)-4-[(E)-3-[(2R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]oxy-3-oxoprop-1-enyl]-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylate
• InChI: InChI=1S/C38H34O16/c1-50-36(47)29(15-18-3-8-22(39)26(43)13-18)52-31(46)12-7-20-5-11-25(42)35-32(20)33(34(54-35)21-6-10-24(41)28(45)17-21)38(49)53-30(37(48)51-2)16-19-4-9-23(40)27(44)14-19/h3-14,17,29-30,33-34,39-45H,15-16H2,1-2H3/b12-7+/t29-,30-,33+,34-/m1/s1
• InChIKey: DHYLGBJCEGEBGQ-QHIXFNMVSA-N
• SMILES: COC(=O)[C@@H](CC1=CC(=C(C=C1)O)O)OC(=O)/C=C/C2=C3[C@@H]([C@H](OC3=C(C=C2)O)C4=CC(=C(C=C4)O)O)C(=O)O[C@H](CC5=CC(=C(C=C5)O)O)C(=O)OC

Dimethyl lithospermate B（Cat No.:R072486）is a derivative of lithospermate B, a polyphenolic compound isolated from Salvia miltiorrhiza (Danshen), a traditional Chinese medicinal herb. It exhibits strong antioxidant, cardioprotective, and neuroprotective activities by scavenging reactive oxygen species and modulating mitochondrial and vascular function. Dimethyl lithospermate B has been studied for improving endothelial function, preventing atherosclerosis, and protecting against ischemia-reperfusion injury. Its neuroprotective properties suggest potential in treating neurodegenerative diseases. As a stabilized esterified form, it offers enhanced bioavailability, making it a valuable compound for cardiovascular and neurological research.