Dimethyl biphenyl-4,4/'-dicarboxylate

• CAT Number: R065647
• CAS Number: 792-74-5
• Molecular Formula: C16H14O4
• Molecular Weight: 270.284
• Purity: ≥95%
• Synonyms: Biphenyl dimethyl dicarboxylate
• Storage: -20°C
• IUPAC Name: methyl 4-(4-methoxycarbonylphenyl)benzoate
• InChI: InChI=1S/C16H14O4/c1-19-15(17)13-7-3-11(4-8-13)12-5-9-14(10-6-12)16(18)20-2/h3-10H,1-2H3
• InChIKey: BKRIRZXWWALTPU-UHFFFAOYSA-N
• SMILES: COC(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)OC

Dimethyl biphenyl-4,4/’-dicarboxylate is a planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis. At 250 µg/ml, it has been shown to stimulate JAK/STAT signaling and to induce the expression of interferon-α stimulated genes in a HepG2 cell line.

Reference

1.Joo, S.S.,Won, T.J.,Kim, M.J., et al. Interferon signal transduction of biphenyl dimethyl dicarboxylate/amantadine and anti-HBV activity in HepG2 2.2.15. Archives of Pharmacal Research 29(5), 405-411 (2006).