For research use only. Not for therapeutic Use.
Diisopropyl azodicarboxylate (Cat No.:R059498) is an orange to red liquid with the molecular formula C8H14N2O4, commonly used as an oxidizing agent and coupling reagent in organic synthesis. It is best known for its role in the Mitsunobu reaction, where it facilitates the conversion of alcohols into various functional groups via nucleophilic substitution. DIAD contains two isopropyl ester groups and an azo linkage, making it both electrophilic and thermally sensitive. It is valued for its mild reaction conditions and compatibility with a wide range of substrates in pharmaceutical and fine chemical development.
| CAS Number | 2446-83-5 |
| Synonyms | 1,2-Diazenedicarboxylic Acid 1,2-Bis(1-methylethyl) Ester; Azodiformic Acid Diisopropyl Ester; DIAD; Diisopropyl Azodiformate; Diisopropyl diazodicarboxylate; |
| Molecular Formula | C₈H₁₄N₂O₄ |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | propan-2-yl (NE)-N-propan-2-yloxycarbonyliminocarbamate |
| InChI | InChI=1S/C8H14N2O4/c1-5(2)13-7(11)9-10-8(12)14-6(3)4/h5-6H,1-4H3/b10-9+ |
| InChIKey | VVWRJUBEIPHGQF-MDZDMXLPSA-N |
| SMILES | CC(C)OC(=O)/N=N/C(=O)OC(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
