Dihydrolanosterol

For research use only. Not for therapeutic Use.

  • CAT Number: R021697
  • CAS Number: 79-62-9
  • Molecular Formula: C30H52O
  • Molecular Weight: 428.73
  • Purity: ≥95%
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Dihydrolanosterol (Cat No.: R021697) is a sterol intermediate in the cholesterol and steroid biosynthesis pathway, derived from the reduction of lanosterol. Structurally, it retains the tetracyclic sterane backbone but with modified double bonds, reflecting its transitional role in sterol metabolism. It is studied mainly in the context of enzymatic steps involving lanosterol reductases and cytochrome P450 enzymes. While not a major end-product, dihydrolanosterol provides insights into sterol processing, lipid homeostasis, and the regulation of cholesterol biosynthesis in mammalian and microbial systems.


CAS Number 79-62-9
Synonyms

(3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol

Molecular Formula C30H52O
Purity ≥95%
InChI InChI=1S/C30H52O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h20-22,25-26,31H,9-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
InChIKey MBZYKEVPFYHDOH-BQNIITSRSA-N
SMILES CC(C)CCCC(C)C1CCC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C
Reference

[1]. Lepesheva GI, Waterman MR. Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms. Biochim Biophys Acta. 2007;1770(3):467-477.
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