For research use only. Not for therapeutic Use.
Dihydrolanosterol (Cat No.: R021697) is a sterol intermediate in the cholesterol and steroid biosynthesis pathway, derived from the reduction of lanosterol. Structurally, it retains the tetracyclic sterane backbone but with modified double bonds, reflecting its transitional role in sterol metabolism. It is studied mainly in the context of enzymatic steps involving lanosterol reductases and cytochrome P450 enzymes. While not a major end-product, dihydrolanosterol provides insights into sterol processing, lipid homeostasis, and the regulation of cholesterol biosynthesis in mammalian and microbial systems.
CAS Number | 79-62-9 |
Synonyms | (3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol |
Molecular Formula | C30H52O |
Purity | ≥95% |
InChI | InChI=1S/C30H52O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h20-22,25-26,31H,9-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1 |
InChIKey | MBZYKEVPFYHDOH-BQNIITSRSA-N |
SMILES | CC(C)CCCC(C)C1CCC2(C1(CCC3=C2CCC4C3(CCC(C4(C)C)O)C)C)C |
Reference | [1]. Lepesheva GI, Waterman MR. Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms. Biochim Biophys Acta. 2007;1770(3):467-477. |
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