For research use only. Not for therapeutic Use.
Dihydrocucurbitacin B（Cat No.:M058440）is a natural tetracyclic triterpenoid belonging to the cucurbitacin family, isolated from plants such as cucurbits and Trichosanthes species. It is known for its potent anticancer, anti-inflammatory, and hepatoprotective activities. Mechanistically, dihydrocucurbitacin B disrupts signaling pathways like JAK/STAT3 and NF-κB, leading to inhibition of tumor cell proliferation, induction of apoptosis, and suppression of inflammatory responses. It has been studied for potential therapeutic applications in cancer, liver disorders, and inflammatory diseases. As a bioactive natural product, it serves as a promising lead compound in drug discovery research.
| CAS Number | 13201-14-4 |
| Synonyms | [(6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxoheptan-2-yl] acetate |
| Molecular Formula | C32H48O8 |
| Purity | ≥95% |
| IUPAC Name | [(6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxoheptan-2-yl] acetate |
| InChI | InChI=1S/C32H48O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,19-22,25,34-35,39H,11-16H2,1-9H3/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1 |
| InChIKey | QZJJDOYZVRUEDY-NRNCYQGDSA-N |
| SMILES | CC(=O)OC(C)(C)CCC(=O)[C@@](C)([C@H]1[C@@H](C[C@@]2([C@@]1(CC(=O)[C@@]3([C@H]2CC=C4[C@H]3C[C@@H](C(=O)C4(C)C)O)C)C)C)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
