For research use only. Not for therapeutic Use.
Dihydrexidine hydrochloride(CAT: I026138) is a potent, high-affinity dopamine D₁ receptor full agonist with selectivity over D₂-like receptors. It exhibits nanomolar binding affinity and robust efficacy in activating D₁-mediated signaling pathways. As one of the earliest high-efficacy D₁ agonists, dihydrexidine has been widely studied for its effects on motor function, cognition, and neuropsychiatric disorders. In preclinical models, it improves working memory and enhances cortical activity, while also showing potential to alleviate Parkinsonian motor deficits. Its ability to cross the blood–brain barrier and selectively engage D₁ receptors makes dihydrexidine a valuable pharmacological tool for dopaminergic and neurological research.
| CAS Number | 137417-08-4 |
| Molecular Formula | C17H18ClNO2 |
| Purity | ≥95% |
| IUPAC Name | (6aR,12bS)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine-10,11-diol;hydrochloride |
| InChI | InChI=1S/C17H17NO2.ClH/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14;/h1-4,7-8,14,17-20H,5-6,9H2;1H/t14-,17-;/m1./s1 |
| InChIKey | IJYUPBNUPIRQEP-SATBOSKTSA-N |
| SMILES | C1CC2=CC(=C(C=C2[C@@H]3[C@@H]1NCC4=CC=CC=C34)O)O.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
