For research use only. Not for therapeutic Use.
Digoxigenin bisdigitoxoside(CAT: R012542) is a cardiac glycoside derivative with demonstrated cytotoxic and anticancer activity. Structurally based on digoxigenin, this compound exerts its biological effects by disrupting cellular ion homeostasis and signaling pathways, leading to apoptosis and inhibition of cancer cell proliferation. Its potent cytotoxic properties make it a valuable candidate for anticancer drug research, particularly in studies exploring glycoside-induced cell death mechanisms. Digoxigenin bisdigitoxoside is useful in evaluating the therapeutic potential of cardiac glycoside analogs and their role in oncology, pharmacology, and cell signaling.
| CAS Number | 5297-05-2 |
| Synonyms | 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one |
| Molecular Formula | C35H54O11 |
| Purity | ≥95% |
| IUPAC Name | 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one |
| InChI | InChI=1S/C35H54O11/c1-17-31(40)25(36)14-30(43-17)46-32-18(2)44-29(15-26(32)37)45-21-7-9-33(3)20(12-21)5-6-23-24(33)13-27(38)34(4)22(8-10-35(23,34)41)19-11-28(39)42-16-19/h11,17-18,20-27,29-32,36-38,40-41H,5-10,12-16H2,1-4H3/t17-,18-,20-,21+,22-,23-,24+,25+,26+,27-,29+,30+,31-,32-,33+,34+,35+/m1/s1 |
| InChIKey | NTSBMKIZRSBFTA-AIDOXSFESA-N |
| SMILES | CC1C(C(CC(O1)OC2C(OC(CC2O)OC3CCC4(C(C3)CCC5C4CC(C6(C5(CCC6C7=CC(=O)OC7)O)C)O)C)C)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
