Diflapolin（Cat No.:I026126）is a potent dual inhibitor targeting microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase-activating protein (FLAP), two key enzymes in the arachidonic acid pathway involved in inflammation and pain signaling. By simultaneously blocking the synthesis of prostaglandin E2 (PGE2) and leukotrienes, Diflapolin exerts strong anti-inflammatory effects without affecting COX-1 or COX-2, reducing gastrointestinal and cardiovascular side effects. It has demonstrated efficacy in preclinical models of inflammatory diseases. Diflapolin is a valuable pharmacological tool for studying inflammation, pain mechanisms, and for developing safer, targeted anti-inflammatory therapeutics.