Diethyl fluoromalonate

• CAT Number: L011561
• CAS Number: 685-88-1
• Molecular Formula: C7H11FO4
• Molecular Weight: 178.16
• Purity: ≥95%
• IUPAC Name: diethyl 2-fluoropropanedioate
• InChI: InChI=1S/C7H11FO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3
• InChIKey: GOWQBFVDZPZZFA-UHFFFAOYSA-N
• SMILES: CCOC(=O)C(C(=O)OCC)F

Diethyl fluoromalonate（Cat No.:L011561）is an organofluorine compound with the formula C7H11FO4, consisting of a malonate core substituted with a fluorine atom and two ethyl ester groups. It is a versatile reagent in organic synthesis, particularly useful as a fluorinated building block in the preparation of pharmaceuticals, agrochemicals, and fluorinated amino acids. The fluorine atom introduces unique electronic effects, enhancing biological activity and metabolic stability in target molecules. Its reactivity allows for alkylation, condensation, and decarboxylation reactions, making it a valuable intermediate for incorporating fluorine into complex molecular frameworks.