Diethyl 2-oxopentanedioate

• CAT Number: L042971
• CAS Number: 5965-53-7
• Molecular Formula: C9H14O5
• Molecular Weight: 202.20
• Purity: ≥95%
• IUPAC Name: diethyl 2-oxopentanedioate
• InChI: InChI=1S/C9H14O5/c1-3-13-8(11)6-5-7(10)9(12)14-4-2/h3-6H2,1-2H3
• InChIKey: NGRAIMFUWGFAEM-UHFFFAOYSA-N
• SMILES: CCOC(=O)CCC(=O)C(=O)OCC

Diethyl 2-oxopentanedioate（Cat No.:L042971）, also known as diethyl α-oxoglutarate, is a β-keto diester with the molecular formula C9H14O5. It features a five-carbon backbone with two ester groups and a central ketone, making it a highly reactive intermediate in organic synthesis. This compound is widely used in the preparation of heterocycles, pharmaceuticals, and fine chemicals through condensation, alkylation, and cyclization reactions. Its structure mimics α-ketoglutarate, a key metabolite in the Krebs cycle, making it useful in biochemical studies. It also serves as a precursor in the synthesis of amino acids and complex natural products.