For research use only. Not for therapeutic Use.
Dicloromezotiaz（Cat No.:I044147）is a thiazide-like diuretic used primarily to manage hypertension and edema associated with conditions such as heart failure and renal disorders. It works by inhibiting sodium and chloride reabsorption in the distal convoluted tubules of the kidney, promoting the excretion of sodium, water, and accompanying electrolytes. This diuretic action reduces plasma volume and blood pressure. Dicloromezotiaz may also exhibit mild vasodilatory effects, enhancing its antihypertensive properties. It is administered orally and requires monitoring for potential side effects, including electrolyte imbalances, dehydration, and increased blood glucose or uric acid levels.
| CAS Number | 1263629-39-5 |
| Synonyms | 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-(3,5-dichlorophenyl)-9-methyl-4-oxopyrido[1,2-a]pyrimidin-1-ium-2-olate |
| Molecular Formula | C19H12Cl3N3O2S |
| Purity | ≥95% |
| IUPAC Name | 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-(3,5-dichlorophenyl)-9-methyl-4-oxopyrido[1,2-a]pyrimidin-1-ium-2-olate |
| InChI | InChI=1S/C19H12Cl3N3O2S/c1-10-3-2-4-24-16(10)25(9-14-8-23-19(22)28-14)18(27)15(17(24)26)11-5-12(20)7-13(21)6-11/h2-8H,9H2,1H3 |
| InChIKey | PVDQXPBKBSCNJZ-UHFFFAOYSA-N |
| SMILES | CC1=CC=CN2C1=[N+](C(=C(C2=O)C3=CC(=CC(=C3)Cl)Cl)[O-])CC4=CN=C(S4)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
