Diclofenac methyl ester

• CAT Number: R012527
• CAS Number: 15307-78-5
• Molecular Formula: C15H13Cl2NO2
• Molecular Weight: 310.18
• Purity: ≥95%
• Synonyms: methyl 2-[2-(2,6-dichloroanilino)phenyl]acetate
• InChI: InChI=1S/C15H13Cl2NO2/c1-20-14(19)9-10-5-2-3-8-13(10)18-15-11(16)6-4-7-12(15)17/h2-8,18H,9H2,1H3
• InChIKey: VETACGBDFVVKGZ-UHFFFAOYSA-N
• SMILES: COC(=O)CC1=CC=CC=C1NC2=C(C=CC=C2Cl)Cl

Diclofenac Methyl Ester (Cat No.: R012527) is a lipophilic derivative of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX-1 and COX-2) to reduce inflammation, pain, and fever. This esterified form enhances membrane permeability and bioavailability, making it useful in prodrug development and pharmacokinetic studies. Diclofenac Methyl Ester is widely applied in inflammation, pain management, and drug delivery research, particularly for improving drug absorption and targeting. It serves as a valuable tool in developing novel NSAID formulations and therapeutic strategies.

Reference

[1]. Fu Q, et al., Biotransformation Changes Bioaccumulation and Toxicity of Diclofenac in Aquatic Organisms. Environ Sci Technol. 2020 Apr 7;54(7):4400-4408.
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