For research use only. Not for therapeutic Use.
(Diacetoxyiodo)benzene（Cat No.:R040198）, also known as PIDA (phenyliodine(III) diacetate), is a hypervalent iodine compound widely used as an oxidizing agent in organic synthesis. It features an iodine center bonded to a phenyl group and two acetate ligands, giving it strong electrophilic properties. PIDA is commonly employed in oxidative coupling, rearrangements, and halogenation reactions. Its mild and selective reactivity makes it valuable in the preparation of complex molecules, particularly in natural product synthesis and medicinal chemistry. PIDA is also favored for its stability and ease of handling in laboratory settings.
| CAS Number | 3240-34-4 |
| Synonyms | (Dihydroxyiodo)benzene; (Diacetoxyiodo)benzene; BAIB; Bis(acetato)phenyliodine; Bis(acetato-κO)phenyliodine; Diacetoxy(phenyl)iodine; Iodobenzene Diacetate; Iodophenyl Diacetate; Iodosobenzene Diacetate; Iodosylbenzene Diacetate; NSC 226375; NSC 2380 |
| Molecular Formula | C10H11IO4 |
| Purity | ≥95% |
| Storage | Desiccate at -20C |
| IUPAC Name | [acetyloxy(phenyl)-lambda3-iodanyl] acetate |
| InChI | InChI=1S/C10H11IO4/c1-8(12)14-11(15-9(2)13)10-6-4-3-5-7-10/h3-7H,1-2H3 |
| InChIKey | ZBIKORITPGTTGI-UHFFFAOYSA-N |
| SMILES | CC(=O)OI(C1=CC=CC=C1)OC(=O)C |
| Reference | <span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>1.<span class=”entryAuthor” style=”box-sizing: border-box; color: rgb(28, 29, 30); font-variant-ligatures: normal; orphans: 2; widows: 2;”><span class=”hlFld-ContribAuthor” style=”box-sizing: border-box;”>Jason Tao, </span><span class=”hlFld-ContribAuthor” style=”box-sizing: border-box;”>Richard Tran, </span><span class=”hlFld-ContribAuthor” style=”box-sizing: border-box;”>Graham K. Murphy, </span></span><span style=”box-sizing: border-box; color: rgb(28, 29, 30); font-variant-ligatures: normal; orphans: 2; widows: 2;”>Dihaloiodoarenes: α,α-Dihalogenation of Phenylacetate Derivatives, </span><span class=”seriesTitle” style=”box-sizing: border-box; color: rgb(28, 29, 30); font-variant-ligatures: normal; orphans: 2; widows: 2;”>Journal of the American Chemical Society, </span><span class=”doi” style=”box-sizing: border-box; color: rgb(28, 29, 30); font-variant-ligatures: normal; orphans: 2; widows: 2;”>10.1021/ja408678p, </span><span class=”volume” style=”box-sizing: border-box; color: rgb(28, 29, 30); font-variant-ligatures: normal; orphans: 2; widows: 2;”><span style=”box-sizing: border-box;”>135</span>, </span><span class=”issue” style=”box-sizing: border-box; color: rgb(28, 29, 30); font-variant-ligatures: normal; orphans: 2; widows: 2;”>44, </span><span class=”page-range” style=”box-sizing: border-box; color: rgb(28, 29, 30); font-variant-ligatures: normal; orphans: 2; widows: 2;”>(16312-16315), </span></span></span><span class=”pub-date” style=”box-sizing: border-box; color: rgb(28, 29, 30); font-family: "Open Sans", icomoon, sans-serif; font-size: 14px; font-variant-ligatures: normal; orphans: 2; widows: 2;”><span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>(2013).</span></span><br /> |
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