Di-O-methyl-β-cyclodextrin

• CAT Number: R013512
• CAS Number: 51166-71-3
• Molecular Formula: C56H98O35
• Molecular Weight: 1331.36
• Purity: ≥95%
• Synonyms: 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-Tetradeca-O-methyl-β-cyclodextrin; 2,6-Dimethyl-β-cyclodextrin; Dimeb; Hepta-(2,6-di-oxy-methyl)-β-cyclodextrin; Heptakis(2,6-di-O-methyl)-β-cyclodextrin; Tetradeca-O-methyl-β-cyclodextrin; Tetradecakis-2,6-O
• Storage: -20°C
• IUPAC Name: (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,37R,38S,39R,40S,41R,42S,43R,44S,45R,46S,47R,48S,49R)-37,39,41,43,45,47,49-heptamethoxy-5,10,15,20,25,30,35-heptakis(methoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,38,40,42,44,46,48-heptol
• InChI: InChI=1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1
• InChIKey: QGKBSGBYSPTPKJ-UZMKXNTCSA-N
• SMILES: COCC1C2C(C(C(O1)OC3C(OC(C(C3O)OC)OC4C(OC(C(C4O)OC)OC5C(OC(C(C5O)OC)OC6C(OC(C(C6O)OC)OC7C(OC(C(C7O)OC)OC8C(OC(O2)C(C8O)OC)COC)COC)COC)COC)COC)COC)OC)O

Dimethyl cyclodextrin(CAT: R013512) is a chemically modified cyclodextrin in which hydroxyl groups on the glucose units are methylated to improve solubility and reduce crystallinity. It retains the toroidal structure characteristic of native cyclodextrins, enabling the formation of inclusion complexes with hydrophobic guest molecules. This enhanced solubility profile makes dimethyl cyclodextrin particularly useful in pharmaceutical and biochemical applications, including drug delivery, solubilization of poorly water-soluble compounds, and stabilization of labile molecules. It also finds use in analytical chemistry and material sciences, where it facilitates selective molecular encapsulation, improves bioavailability, and supports advanced formulation strategies in research and development.