Devazepide

• CAT Number: M011517
• CAS Number: 103420-77-5
• Molecular Formula: C25H20N4O2
• Molecular Weight: 408.45
• Purity: ≥95%
• Synonyms: N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
• InChI: InChI=1S/C25H20N4O2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26H,1H3,(H,28,30)/t23-/m1/s1
• InChIKey: NFHRQQKPEBFUJK-HSZRJFAPSA-N
• SMILES: CN1C2=CC=CC=C2C(=N[C@@H](C1=O)NC(=O)C3=CC4=CC=CC=C4N3)C5=CC=CC=C5

Devazepide（Cat No.:M011517）is a potent, selective antagonist of the cholecystokinin type A receptor (CCK-A), widely used as a research tool in gastrointestinal and metabolic studies. By blocking CCK-A receptor activity, it inhibits the effects of cholecystokinin on gallbladder contraction, pancreatic enzyme secretion, and satiety regulation. This makes it valuable for exploring mechanisms of digestion, appetite control, and gut–brain signaling. Additionally, devazepide has been studied for potential therapeutic roles in obesity, gastrointestinal disorders, and pancreatic disease. Its high specificity enables detailed investigation of CCK-mediated physiological and pathological processes.