Destruxin A

• CAT Number: R000167
• CAS Number: 6686-70-0
• Molecular Formula: C29H47N5O7
• Molecular Weight: 577.71
• Purity: ≥95%
• Synonyms: (3R,10S,13S,16S,19S)-16-[(2S)-butan-2-yl]-10,11,14-trimethyl-13-propan-2-yl-3-prop-2-enyl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone
• InChI: InChI=1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)/t18-,19-,20-,21+,23-,24-/m0/s1
• InChIKey: XIYSEKITPHTMJT-OCCJOITDSA-N
• SMILES: CC[C@H](C)[C@H]1C(=O)N([C@H](C(=O)N([C@H](C(=O)NCCC(=O)O[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)CC=C)C)C)C(C)C)C

Destruxin A（Cat No.:R000167）is a cyclodepsipeptide mycotoxin produced by entomopathogenic fungi such as Metarhizium anisopliae. It is well known for its insecticidal activity, disrupting calcium signaling, mitochondrial function, and immune responses in insects, ultimately leading to paralysis and death. Beyond its role as a natural biopesticide, Destruxin A exhibits immunosuppressive, antiviral, and anticancer properties, making it of interest in biomedical research. Its unique mode of action highlights potential for agricultural pest control while also serving as a valuable tool in pharmacology and natural product chemistry investigations.