Desmethylene Paroxetine (hydrochloride)

• CAT Number: R065121
• CAS Number: 1394861-12-1
• Molecular Formula: C18H20FNO3 • HCl
• Molecular Weight: 353.80
• Purity: ≥95%
• Synonyms: 4-[[(3S,4R)-4-(4-fluorophenyl)-3-piperidinyl]methoxy]-1,2-benzenediol, monohydrochloride
• Target: Drug Metabolite
• Storage: -20°C
• IUPAC Name: 4-[[(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methoxy]benzene-1,2-diol;hydrochloride
• InChI: InChI=1S/C18H20FNO3.ClH/c19-14-3-1-12(2-4-14)16-7-8-20-10-13(16)11-23-15-5-6-17(21)18(22)9-15;/h1-6,9,13,16,20-22H,7-8,10-11H2;1H/t13-,16-;/m0./s1
• InChIKey: GIPUDSSHAJOHQK-LINSIKMZSA-N
• SMILES: C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC(=C(C=C3)O)O.Cl

Desmethylene Paroxetine (Hydrochloride)（Cat No.:R065121）is an active metabolite and structural analog of the selective serotonin reuptake inhibitor (SSRI) paroxetine. Lacking the methylene bridge present in the parent compound, it is used in pharmacological and metabolic studies to explore the mechanism of action, bioactivity, and degradation pathways of paroxetine. This compound is valuable in neurochemical research for assessing serotonin transporter binding and central nervous system effects. Supplied as a stable hydrochloride salt and at high purity, it is ideal for preclinical studies in psychopharmacology and drug metabolism research.