For research use only. Not for therapeutic Use.
Desipramine-d₄（Cat No.:R006740）is a deuterated analog of desipramine, a tricyclic antidepressant, in which four hydrogen atoms are replaced with deuterium. This isotopically labeled compound is primarily used as an internal standard in LC-MS/MS for precise quantification of desipramine in biological samples. It retains the pharmacological properties of the parent drug, which acts by inhibiting norepinephrine reuptake in the central nervous system. The incorporation of deuterium enhances analytical accuracy without altering biological activity. Desipramine-d₄ is essential in pharmacokinetic, bioequivalence, and drug metabolism studies, particularly in clinical and pharmaceutical research.
| CAS Number | 61361-34-0 |
| Synonyms | N-methyl-3-(1,3,8,10-tetradeuterio-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propan-1-amine;hydrochloride |
| Molecular Formula | C18H19D4ClN2 |
| Purity | ≥95% |
| IUPAC Name | N-methyl-3-(1,3,8,10-tetradeuterio-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propan-1-amine;hydrochloride |
| InChI | InChI=1S/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H/i2D,3D,9D,10D; |
| InChIKey | XAEWZDYWZHIUCT-TUJKZWLVSA-N |
| SMILES | [2H]C1=CC(=C2C(=C1)CCC3=CC(=CC(=C3N2CCCNC)[2H])[2H])[2H].Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
