Demethoxydeacetoxypseudolaric acid B

• CAT Number: R003306
• CAS Number: 82508-36-9
• Molecular Formula: C20H24O7
• Molecular Weight: 376.40
• Purity: ≥95%
• Synonyms: (1R,7S,8R,9R)-9-[(1E,3E)-4-carboxypenta-1,3-dienyl]-7-hydroxy-9-methyl-11-oxo-10-oxatricyclo[6.3.2.01,7]tridec-3-ene-4-carboxylic acid
• InChI: InChI=1S/C20H24O7/c1-12(15(21)22)4-3-8-18(2)14-7-10-19(17(25)27-18)9-5-13(16(23)24)6-11-20(14,19)26/h3-5,8,14,26H,6-7,9-11H2,1-2H3,(H,21,22)(H,23,24)/b8-3+,12-4+/t14-,18+,19+,20-/m0/s1
• InChIKey: QPFFEVMIQIJTGZ-XYWPTNBISA-N
• SMILES: C/C(=C\C=C\[C@@]1([C@@H]2CC[C@@]3([C@@]2(CCC(=CC3)C(=O)O)O)C(=O)O1)C)/C(=O)O

Demethoxydeacetoxypseudolaric acid B（Cat No.:R003306）is a diterpene acid derivative isolated from Pseudolarix kaempferi, a plant traditionally used in Chinese medicine. Structurally related to pseudolaric acid B, this compound lacks methoxy and acetoxy groups, which influences its bioactivity profile. It exhibits potent antifungal, antiproliferative, and anti-inflammatory properties, acting through mechanisms such as microtubule disruption and inhibition of cell division. Demethoxydeacetoxypseudolaric acid B is of interest in cancer research for its ability to induce apoptosis and suppress tumor cell growth. Its diverse pharmacological effects highlight its promise in natural product-based therapeutic development.