For research use only. Not for therapeutic Use.
Deltasonamide 1 TFA (Cat No.: I042501) is the trifluoroacetate salt form of a synthetic peptide modulator targeting the δ-opioid receptor (DOR), a G protein-coupled receptor involved in pain modulation, mood regulation, and neuroprotection. As a selective δ-opioid receptor agonist or antagonist (depending on its design), Deltasonamide 1 is used in pharmacological studies to investigate DOR-mediated signaling pathways. The TFA salt enhances its solubility and stability. This compound is valuable for exploring therapeutic strategies for chronic pain, depression, and neurodegenerative disorders.
| CAS Number | 2235358-73-1 |
| Synonyms | 4-N-[(4-chlorophenyl)methyl]-4-N-cyclopentyl-1-N-[[2-(methylamino)pyrimidin-4-yl]methyl]-1-N-(piperidin-4-ylmethyl)benzene-1,4-disulfonamide;2,2,2-trifluoroacetic acid |
| Molecular Formula | C32H40ClF3N6O6S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C30H39ClN6O4S2.C2HF3O2/c1-32-30-34-19-16-26(35-30)22-36(20-24-14-17-33-18-15-24)42(38,39)28-10-12-29(13-11-28)43(40,41)37(27-4-2-3-5-27)21-23-6-8-25(31)9-7-23;3-2(4,5)1(6)7/h6-13,16,19,24,27,33H,2-5,14-15,17-18,20-22H2,1H3,(H,32,34,35);(H,6,7) |
| InChIKey | QLWRGHQLCOMPMZ-UHFFFAOYSA-N |
| SMILES | CNC1=NC=CC(=N1)CN(CC2CCNCC2)S(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)N(CC4=CC=C(C=C4)Cl)C5CCCC5.C(=O)(C(F)(F)F)O |
| Reference | [1]. Pablo Martín-Gago, et al. A PDE6δ-KRas Inhibitor Chemotype With Up to Seven H-Bonds and Picomolar Affinity That Prevents Efficient Inhibitor Release by Arl2. Angew Chem Int Ed Engl. 2017 Feb 20;56(9):2423-2428. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
