Dehydroabietic Acid

• CAT Number: R055278
• CAS Number: 1740-19-8
• Molecular Formula: C20H28O2
• Molecular Weight: 300.44
• Purity: ≥95%
• Synonyms: (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic Acid; 13-Isopropylpodocarpa-8,11,13-trien-15-oic Acid; (+)-Dehydroabietic acid; Abieta-8,11,13-trien-18-oic acid; NSC 2952; [1R-(1α,4aβ,10aα)]-1,2,3,
• Target: Vitamin D Related/Nuclear Receptor
• Storage: -20°C
• IUPAC Name: (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxylic acid
• InChI: InChI=1S/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s1
• InChIKey: NFWKVWVWBFBAOV-MISYRCLQSA-N
• SMILES: CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)C(=O)O)C

Dehydroabietic acid (Cat No.: R055278) is a naturally occurring tricyclic diterpenoid resin acid with the molecular formula C₂₀H₂₈O₂. Derived primarily from conifer resins such as rosin, it features an abietane skeleton with a carboxylic acid group and a double bond in the C-ring. Dehydroabietic acid exhibits antimicrobial, anti-inflammatory, and antifungal properties and is used in the synthesis of bioactive compounds, varnishes, and metal soaps. It also serves as a chemical marker in environmental studies to trace biomass combustion and resin-based industrial emissions.

Reference

1.Kang, Min‐Sook, et al. "Dehydroabietic acid, a diterpene, improves diabetes and hyperlipidemia in obese diabetic KK‐Ay mice." BioFactors 35.5 (2009): 442-448.
2.Brownlee, B., et al. "Distribution of dehydroabietic acid in sediments adjacent to a kraft pulp and paper mill." Journal of the Fisheries Board of Canada 34.6 (1977): 838-843.