For research use only. Not for therapeutic Use.
DDR1-IN-5（Cat No.:I015272）is a selective inhibitor of discoidin domain receptor 1 (DDR1), a collagen-activated receptor tyrosine kinase implicated in cancer, fibrosis, and chronic inflammatory diseases. By targeting DDR1 activity, this compound interferes with signaling pathways that regulate extracellular matrix remodeling, cell adhesion, proliferation, and survival. DDR1-IN-5 is widely used as a research tool to study the role of DDR1 in pathological processes, particularly tumor progression and fibrotic tissue responses. Its specificity provides value in chemical biology, drug discovery, and the development of targeted therapeutic approaches.
| CAS Number | 2416022-90-5 |
| Synonyms | 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[5-(trifluoromethyl)pyridin-3-yl]-1,2-benzoxazol-3-amine |
| Molecular Formula | C22H13F3N6O |
| Purity | ≥95% |
| IUPAC Name | 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[5-(trifluoromethyl)pyridin-3-yl]-1,2-benzoxazol-3-amine |
| InChI | InChI=1S/C22H13F3N6O/c1-13-4-6-18-20(17(13)7-5-16-12-27-19-3-2-8-28-31(16)19)32-30-21(18)29-15-9-14(10-26-11-15)22(23,24)25/h2-4,6,8-12H,1H3,(H,29,30) |
| InChIKey | LGHRUPKASNQBFS-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(C=C1)C(=NO2)NC3=CN=CC(=C3)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
