For research use only. Not for therapeutic Use.
DC-LC3in-D5（Cat No.:I045226）is a potent, selective inhibitor of the interaction between LC3 (microtubule-associated protein 1A/1B-light chain 3) and its binding partners, disrupting autophagosome formation and autophagy flux. By blocking LC3-mediated cargo recruitment, DC-LC3in-D5 impairs degradation of targeted cellular components, enabling detailed investigation of autophagy regulation. It is a valuable chemical biology tool for studying the role of LC3–protein interactions in cellular homeostasis, stress responses, and disease progression. DC-LC3in-D5 holds potential for therapeutic exploration in cancer, neurodegeneration, and infectious diseases where dysregulated autophagy contributes to pathology.
| CAS Number | 2868312-73-4 |
| Synonyms | 5-(2,3-dichlorophenyl)-3-hydroxy-2-(2-morpholin-4-ylethyliminomethyl)cyclohex-2-en-1-one |
| Molecular Formula | C19H22Cl2N2O3 |
| Purity | ≥95% |
| IUPAC Name | 5-(2,3-dichlorophenyl)-3-hydroxy-2-(2-morpholin-4-ylethyliminomethyl)cyclohex-2-en-1-one |
| InChI | InChI=1S/C19H22Cl2N2O3/c20-16-3-1-2-14(19(16)21)13-10-17(24)15(18(25)11-13)12-22-4-5-23-6-8-26-9-7-23/h1-3,12-13,24H,4-11H2 |
| InChIKey | IYDBJXOPTZDWCZ-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCN=CC2=C(CC(CC2=O)C3=C(C(=CC=C3)Cl)Cl)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
