dBET6

  • CAT Number: I020016
  • CAS Number: 1950634-92-0
  • Molecular Formula: C₄₂H₄₅ClN₈O₇S
  • Molecular Weight: 841.37
  • Purity: ≥95%
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DBET6 (Cat. No: I020016) is a BET degrading enzyme based on PROTAC ‘s strong, selective, and cell permeability, and can also induce c-MYC down-regulation and apoptosis. It is effective in most cancer cell lines, and dBET6 has a significant degradation effect in cells at concentrations below the nanomolar level.

Catalog Number I020016
CAS Number 1950634-92-0
Molecular Formula

C₄₂H₄₅ClN₈O₇S

Purity 95%
Reference

[1]. Winter GE, et al. BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment. Mol Cell. 2017 Jul 6;67(1):5-18.e19.

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