For research use only. Not for therapeutic Use.
DATPT (Cat No.:I044146) is a small-molecule compound known for its potent inhibition of GTP cyclohydrolase I (GTPCH1), the rate-limiting enzyme in the biosynthesis of tetrahydrobiopterin (BH4). BH4 is a crucial cofactor in nitric oxide and neurotransmitter synthesis. By inhibiting GTPCH1, DATPT reduces BH4 levels, impacting nitric oxide production and monoamine metabolism. It is primarily used in biochemical and pharmacological studies to investigate BH4-related pathways in cardiovascular, neurological, and inflammatory disorders. DATPT is also explored for its role in modulating oxidative stress and immune responses in disease models.
| CAS Number | 2891582-75-3 |
| Synonyms | 2-[2-[2-[[4-(4-tert-butylphenyl)-6-(oxolan-2-ylmethylamino)-1,3,5-triazin-2-yl]amino]ethoxy]ethoxy]ethylazanium;chloride |
| Molecular Formula | C24H39ClN6O3 |
| Purity | ≥95% |
| IUPAC Name | 2-[2-[2-[[4-(4-tert-butylphenyl)-6-(oxolan-2-ylmethylamino)-1,3,5-triazin-2-yl]amino]ethoxy]ethoxy]ethylazanium;chloride |
| InChI | InChI=1S/C24H38N6O3.ClH/c1-24(2,3)19-8-6-18(7-9-19)21-28-22(26-11-14-32-16-15-31-13-10-25)30-23(29-21)27-17-20-5-4-12-33-20;/h6-9,20H,4-5,10-17,25H2,1-3H3,(H2,26,27,28,29,30);1H |
| InChIKey | VKKLNYQJVSKJHM-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C1=CC=C(C=C1)C2=NC(=NC(=N2)NCC3CCCO3)NCCOCCOCC[NH3+].[Cl-] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
