For research use only. Not for therapeutic Use.
Darexaban (Cat No.:I006383) is an oral, direct Factor Xa inhibitor developed as an anticoagulant to prevent thromboembolic events such as stroke and deep vein thrombosis. It selectively blocks the activity of Factor Xa, a key enzyme in the coagulation cascade, thereby inhibiting thrombin generation and clot formation. Darexaban offers predictable pharmacokinetics and does not require routine monitoring, distinguishing it from traditional anticoagulants like warfarin. Though it showed promise in clinical trials for atrial fibrillation and acute coronary syndrome, its development was discontinued. It remains valuable for research in thrombosis and hemostasis.
| CAS Number | 365462-23-3 |
| Synonyms | N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide |
| Molecular Formula | C27H30N4O4 |
| Purity | ≥95% |
| IUPAC Name | N-[2-hydroxy-6-[(4-methoxybenzoyl)amino]phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide |
| InChI | InChI=1S/C27H30N4O4/c1-30-15-4-16-31(18-17-30)21-11-7-19(8-12-21)27(34)29-25-23(5-3-6-24(25)32)28-26(33)20-9-13-22(35-2)14-10-20/h3,5-14,32H,4,15-18H2,1-2H3,(H,28,33)(H,29,34) |
| InChIKey | IJNIQYINMSGIPS-UHFFFAOYSA-N |
| SMILES | CN1CCCN(CC1)C2=CC=C(C=C2)C(=O)NC3=C(C=CC=C3O)NC(=O)C4=CC=C(C=C4)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
