Daratumumab (PBS)

• CAT Number: I040744
• CAS Number: 945721-28-8
• Purity: ≥95%

Daratumumab (PBS)(CAT: I040744) is a recombinant human IgG1κ monoclonal antibody that specifically targets CD38, a surface glycoprotein highly expressed on multiple myeloma cells and other hematologic malignancies. By binding to CD38, Daratumumab induces cell death through multiple mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and apoptosis. Formulated in phosphate-buffered saline (PBS), this version is optimized for laboratory research, including flow cytometry, immunohistochemistry, and in vitro functional assays. Daratumumab (PBS) is a valuable tool for studying CD38 biology, therapeutic resistance, and immune modulation in cancer immunotherapy and hematological research.