• CAT Number: I019323
  • CAS Number: 54863-37-5
  • Molecular Formula: C₄H₇NO₂S
  • Molecular Weight: 133.17
  • Purity: ≥95%
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Dapansutrile(CAT: I019323), also known as MCC950, is a potent and selective inhibitor of the NLRP3 inflammasome, a protein complex involved in the activation of inflammatory responses. By inhibiting the NLRP3 inflammasome, dapansutrile reduces the production of pro-inflammatory cytokines, such as IL-1β and IL-18, thereby exerting anti-inflammatory effects. Additionally, dapansutrile has been shown to possess analgesic activity, potentially providing relief from pain associated with inflammatory conditions. Its oral bioavailability makes dapansutrile a promising candidate for the treatment of inflammatory diseases.

Catalog Number I019323
CAS Number 54863-37-5
Molecular Formula


Purity 95%

[1]. Toldo S, et al. The NLRP3 Inflammasome Inhibitor, Dapansutrile, Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse. J Cardiovasc Pharmacol. 2019 Apr;73(4):215-222.

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