Dapagliflozin Tetraacetate

• CAT Number: R030507
• CAS Number: 461432-25-7
• Molecular Formula: C29H33ClO10
• Molecular Weight: 577.02
• Purity: ≥95%
• Synonyms: (2R,3R,5R,6R)-6-(Acetoxymethyl)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate
• Storage: RT
• IUPAC Name: [(2R,3R,4R,5S,6S)-3,4,5-triacetyloxy-6-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]oxan-2-yl]methyl acetate
• InChI: InChI=1S/C29H33ClO10/c1-6-35-23-10-7-20(8-11-23)13-22-14-21(9-12-24(22)30)26-28(38-18(4)33)29(39-19(5)34)27(37-17(3)32)25(40-26)15-36-16(2)31/h7-12,14,25-29H,6,13,15H2,1-5H3/t25-,26+,27-,28+,29+/m1/s1
• InChIKey: DKOQYKRDCDCNOR-ZCCUTQAASA-N
• SMILES: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)Cl

Dapagliflozin tetraacetate（Cat No.:R030507）is a protected prodrug derivative of dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the treatment of type 2 diabetes. In this form, four hydroxyl groups on the glucose moiety are acetylated, enhancing lipophilicity and stability for synthetic and formulation purposes. The acetate groups can be cleaved under physiological or acidic conditions to release the active dapagliflozin. This compound is primarily used as an intermediate in pharmaceutical research and development to study prodrug behavior, improve bioavailability, or facilitate chemical modifications of SGLT2 inhibitor scaffolds.