For research use only. Not for therapeutic Use.
Danavorexton（Cat No.:I025532）is an investigational orexin-2 receptor (OX2R) agonist developed to promote wakefulness in disorders characterized by excessive daytime sleepiness, such as narcolepsy, idiopathic hypersomnia, and other central hypersomnolence syndromes. By selectively stimulating OX2R, danavorexton enhances arousal pathways in the brain, improving alertness and cognitive performance without the broad stimulant effects of traditional wake-promoting drugs. Administered intravenously in clinical studies, it has shown rapid onset and significant wake-promoting activity. Danavorexton represents a targeted therapeutic approach aimed at restoring orexin signaling and addressing the underlying neurochemical deficits in sleep–wake regulation disorders.
| CAS Number | 2114324-48-8 |
| Molecular Formula | C21H32N2O5S |
| Purity | ≥95% |
| IUPAC Name | methyl (2R,3S)-3-(methanesulfonamido)-2-[(4-phenylcyclohexyl)oxymethyl]piperidine-1-carboxylate |
| InChI | InChI=1S/C21H32N2O5S/c1-27-21(24)23-14-6-9-19(22-29(2,25)26)20(23)15-28-18-12-10-17(11-13-18)16-7-4-3-5-8-16/h3-5,7-8,17-20,22H,6,9-15H2,1-2H3/t17?,18?,19-,20-/m0/s1 |
| InChIKey | UXZAJSZFFARTEI-GUMHCPJTSA-N |
| SMILES | COC(=O)N1CCC[C@@H]([C@@H]1COC2CCC(CC2)C3=CC=CC=C3)NS(=O)(=O)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
