Dalnicastobart

• CAT Number: I040383
• CAS Number: 2642171-59-1
• Purity: ≥95%

Dalnicastobart(CAT: I040383) (LVGN‑7409) is a fully human IgG1κ monoclonal antibody that acts as a potent CD40 agonist, engaging the CD40/TNFRSF5 receptor to activate dendritic cells, macrophages, and T lymphocytes. It is currently in Phase I/II clinical trials for advanced solid tumors, including non–small cell lung cancer, head and neck carcinoma, and lymphoma. Preclinical and early clinical data demonstrate strong immune activation, tumor infiltration, and favorable safety. Supplied at high purity and formulated for research use, Dalnicastobart is ideal for tumor immunology, immune-oncology, and studies of costimulatory signaling and combination therapies.