For research use only. Not for therapeutic Use.
D159687 (CAT: I019143) is a selective inhibitor of phosphodiesterase 4D (PDE4D). PDE4D is an enzyme that plays a role in the breakdown of cyclic adenosine monophosphate (cAMP), a cellular signaling molecule. By inhibiting PDE4D, D159687 increases the levels of cAMP, leading to various downstream effects. As a selective PDE4D inhibitor, D159687 specifically targets this enzyme subtype, potentially offering therapeutic applications in conditions where modulating cAMP levels is desired, such as inflammation, neurological disorders, and respiratory diseases.
| CAS Number | 1155877-97-6 |
| Molecular Formula | C₂₁H₁₉ClN₂O₂ |
| Purity | ≥95% |
| Target | Phosphodiesterase (PDE) |
| Reference | [1]. Zhang C, et al. Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System. Sci Rep. 2017 Jan 5;7:40115. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |